Principal Medical (Science) Director - Neuroimmunology, Multiple Sclerosis

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.  The Opportunity At US Medical (USM), we focus on broadening opportunities for patient access by ensuring that health care stakeholders have the evidence they need on our products and the confidence in that evidence to make informed treatment decisions. As a key pillar in the broader Genentech organization, USM has a pivotal role in bridging internal partner functions (including Research, Product Development, Commercial, and Government Affairs) and collaborating across the dynamic health ecosystem to ultimately deliver better patient outcomes while making care more accessible and affordable for all. We are seeking a visionary medical leader to join the US Medical team at Genentech, focusing on Multiple Sclerosis (MS) and related disorders.  The Principal Medical Director is a player/coach to a team of Medical Directors (MD)/ Medical Science Directors (MSD) and will report to the Therapeutic Area Lead.  By putting patients and science at the center of all actions, they drive and guide medical strategy and tactics aimed at maximizing medical progress. They will play a critical role to establish and maintain professional relationships with key medical experts in their field and will oversee all aspects of medical product support including collaboration with the relevant stakeholders to drive timely data generation and dissemination. They are expected to maintain an in-depth understanding of the medical strategy and relevant clinical and payer issues, while ensuring Genentech's partners understand key trends and shifts in the external healthcare landscape. They understand and evaluate their team and organization’s opportunities and constraints and build capabilities with an enterprise mindset. They serve as the guardian for high standards of compliance, ethics and safety. Key Responsibilities Strategic Leadership: Co-own and execute the medical value proposition and clinical strategies for the MS pipeline, ensuring tactics are aligned with the evolving US healthcare landscape and global Roche goals. Evidence Generation: Drive the design, execution, and monitoring of high-quality Phase IIIb/IV clinical trials, investigator-initiated research, and health economic data analysis to close knowledge gaps. Stakeholder Engagement: Build and maintain professional partnerships with therapeutic area experts, professional societies, and payers to facilitate scientific exchange and collaborative medical progress. Cross-Functional Collaboration: Represent the US Medical function within internal matrix teams and global global organizations, providing clinically meaningful perspectives for regulatory and scientific communications. People Development & Coaching: Act as a player/coach to inspire high performance, identifying development needs and fostering a culture of trust, inclusion, and empowered decision-making. Compliance & Safety: Serve as the guardian for high standards of ethics and safety, ensuring all medical communications and activities strictly adhere to Genentech-Roche policies. Tactical Execution: Lead the efficient implementation of medical tactics, including medical content development, clinical training, and insights generation, while prioritizing work in a fluid, resource-aware environment. Who You Are Qualifications & Experience Advanced Clinical/Science Degree required (e.g. PharmD, PhD, MD etc.) in Neuroimmunology 5+ years of pharmaceutical / biotechnology industry experience Experience in drug development (Phase I-IV), medical writing, and data analysis, with a thorough understanding of US regulatory/FDA requirements. Demonstrated ability to coach, mentor, and develop leaders, and to build relationships with and identify the needs of patients, providers, and payers. Substantive understanding of corporate legal and compliance, including GCP, OIG, and other guiding elements of the business. Proven track record of collaborating, coaching, and influencing outcomes in complex organizations and projects, embracing an agile mindset and new digital healthcare landscapes to serve patient needs. Preferred Qualifications & Experience Extensive experience in Multiple Sclerosis, or related Neurology therapeutic areas. 5+ years of Medical Affairs or Product Development or is a recognized expert in the field Strong academic/teaching background  Previous people management experience  Travel Requirements The position is located in South San Francisco. The position may require up to 25% time traveling.  The expected salary range for this position based on the primary location of South San Francisco, CA is $269,900 - 571,400.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.